ΜΥΟΣΚΕΛΕΤΙΚΑ ΣΥΝΔΡΟΜΑ
PRENATAL DIAGNOSIS
Prenat Diagn 2008; 28: 343–346.
Published online in Wiley InterScience
(www.interscience.wiley.com) DOI: 10.1002/pd.1984
Prenatal diagnosis of clubfoot in low-risk population:
associated anomalies and long-term outcome
M. J. Canto*, S. Cano, J. Palau and F. Ojeda
Hospital General de Granollers, Barcelona, Spain
In conclusion, our study provides outcome data about
fetuses prenatally diagnosed as having clubfoot deformities.
Prenatal detection of clubfoot obliges to perform a
thorough ultrasonographic examination to rule out associated
anomalies and to offer the possibility of karyotype
determination, since one-third of the cases will
be associated with other congenital anomalies. In isolated
cases, parents can be reassured that 90% of the
cases will be confirmed at birth and, also, must be made
aware about the possibility of 2% false-positive cases or
10% disparity on laterality. About 40% of children will
require some additional surgical treatment, in the majority
of cases requiring only one operation, with favorable evolution on long-term follow-up. Prognosis is not worsened
by bilaterality. Since
we have not found any association between laterality and
the presence of associated anomalies, we believe that the
the decision to offer invasive testing should not be in relation
to unilaterality or bilaterality, but on the presence
of associated defects.